T. melanocephalum is a household pest. It can not only invade houses from outside, but nest inside as well and will compromise food sources. It infests buildings in large numbers and has established in temperate locations. It has become established in heated greenhouses where it can become a problem, especially if it defends honeydew producing, plant pests against introduced biological control organisms. T. melanocephalum is capable of transporting pathogenic microbes in hospitals. Some people suffer a slight, red irritation of the skin following contact with this ant (Harris et al. 2005; Nickerson et al. 2003).
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