一般影響
在佛羅里達州，已知蟾鬍鯰已經入侵水產養殖場，進入水池捕食養殖的魚。為了因應此種狀況，養殖業者必須豎立保護的圍欄，以保護這些水池(Nico, 2000)。雖然其他掠食性魚類更加貪吃，蟾鬍鯰已知也會捕食原生種的蝌蚪，尤其對於那些只能在暫時性濕地繁殖的蝌蚪。雖然能避免遭受其他掠食性魚類的捕食，但卻會遭受蟾鬍鯰嚴重的威脅(Baber and Babbitt, 2003)。
地點特有的影響：Philippines 
競爭: Clarias batrachus has have dominated locations of inhabitance and displaced the native catfish (Clarias macrocephalus) in Luzon, Philippines and has spread throughout many other parts of the country (Joshi, undated; Sinohin & Cauterno, 2002). Sri Lanka
競爭: Clarias batrachus threatens endemic fresh water fishes in Sri Lanka (Kotagma & Bambaradeniya, 2006). Florida (USA) (United States (USA))
競爭: Clarias batrachus will outcompete or directly consume several co-occurring native species in Florida. Resident centrarchids, freshwater sunfish, and native catfish species appear particularly susceptible to impacts from this invader. C. batrachus can also negatively impact native amphibian populations by preying on tadpoles (Masterson, 2007).
經濟 /民生: Clarias batrachus in South Florida are known to invade commercial aquaculture facilities, often consuming vast numbers of the stocks of fishes (Robins, undated).
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